Description

(3-(tert-Butylcarbamoyl)-5-Fluorophenyl)Boronic Acid is a high-value, synthetically versatile organoboron compound. It serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions to form carbon-carbon bonds. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing biaryl structures via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require the incorporation of fluorinated phenyl and amide motifs.
• Material Science: Employed in the creation of novel organic electronic materials, ligands for catalysts, and specialty polymers.
• Chemical Synthesis: Acts as a versatile boronic acid reagent for constructing molecular libraries and exploring new chemical space in medicinal chemistry.
• Bioconjugation: Potential use in developing diagnostic probes and bioconjugates due to its reactive boronic acid group.

Basic Information

Product Name	(3-(tert-Butylcarbamoyl)-5-Fluorophenyl)Boronic Acid
CAS No.	1704082-27-8
Molecular Formula	C₁₁H₁₅BFNO₃
Molecular Weight	239.06 g/mol
Synonyms	5-Fluoro-3-[(2-methylpropan-2-yl)carbamoyl]phenylboronic acid; N-tert-Butyl-5-fluoro-3-boronobenzamide; 3-Borono-5-fluoro-N-(tert-butyl)benzamide; (5-Fluoro-3-((tert-butylcarbamoyl))phenyl)boronic acid; B-[3-[(1,1-Dimethylethyl)amino]carbonyl]-5-fluorophenyl]boronic acid
EINECS	Contact for details

Quality Control

Our (3-(tert-Butylcarbamoyl)-5-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high-purity standards required for research and scale-up. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.