Description

(3-Fluoro-5-(4-Methylpiperazine-1-Carbonyl)Phenyl)Boronic Acid is a high-value, multifunctional boronic acid derivative designed for advanced synthetic chemistry. Its core value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a 4-methylpiperazine-carbonyl moiety that offers enhanced solubility and potential for further derivatization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecular architectures in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, enabling the construction of biaryl and heterobiaryl structures prevalent in modern medicinal chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and piperazine motifs for bioactivity.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs, where the boronic acid group facilitates polymerization or functionalization.
• Chemical Biology Probe Development: Useful for creating tagged molecules or affinity ligands due to the reactive handle provided by the boronic acid group.
• Library Synthesis for High-Throughput Screening: An important reagent for generating diverse compound libraries in early-stage drug discovery.

Basic Information

Product Name	(3-Fluoro-5-(4-Methylpiperazine-1-Carbonyl)Phenyl)Boronic Acid
CAS No.	1704082-15-4
Molecular Formula	C13H18BFN2O3
Molecular Weight	280.11 g/mol
Synonyms	[3-Fluoro-5-[(4-methyl-1-piperazinyl)carbonyl]phenyl]boronic acid; B-[3-Fluoro-5-[(4-methyl-1-piperazinyl)carbonyl]phenyl]boronic acid; (3-Fluoro-5-((4-methylpiperazine-1-carbonyl)phenyl)boronic acid; 3-Fluoro-5-(4-methylpiperazine-1-carbonyl)benzeneboronic acid; Boronic acid, B-[3-fluoro-5-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-; 1704082-15-4; Pharmaceutical Intermediate CAS 1704082-15-4
EINECS	Contact for details

Quality Control

Our (3-Fluoro-5-(4-Methylpiperazine-1-Carbonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for critical synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.