Description

(3-Fluoro-4-(3-(4-Methylpiperazin-1-Yl)Propoxy)Phenyl)Boronic Acid Hydrochloride is a high-value, synthetically versatile boronic acid derivative, essential as a key building block in modern organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is critically needed by pharmaceutical R&D teams and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient and selective formation of biaryl and heterobiaryl structures, which are prevalent pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects.

Basic Information

Product Name	(3-Fluoro-4-(3-(4-Methylpiperazin-1-Yl)Propoxy)Phenyl)Boronic Acid Hydrochloride
CAS No.	1704082-06-3
Molecular Formula	C14H22BFN2O3 · HCl
Molecular Weight	339.61 g/mol (Free base: 304.15)
Synonyms	[3-Fluoro-4-[3-(4-methyl-1-piperazinyl)propoxy]phenyl]boronic acid hydrochloride; 4-(3-(4-Methylpiperazin-1-yl)propoxy)-3-fluorophenylboronic acid HCl; B-[3-Fluoro-4-[3-(4-methyl-1-piperazinyl)propoxy]phenyl]boronic acid hydrochloride; (3-Fluoro-4-(3-(4-methylpiperazin-1-yl)propoxy)phenyl)boronic acid hydrochloride; Boronic acid, B-[3-fluoro-4-[3-(4-methyl-1-piperazinyl)propoxy]phenyl]-, hydrochloride; CAS 1704082-06-3; Pharmaceutical Intermediate 1704082-06-3
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-(3-(4-Methylpiperazin-1-Yl)Propoxy)Phenyl)Boronic Acid Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.