Description

(3-(((2,4-Dimethoxybenzyl)Amino)Methyl)-5-Fluorophenyl)Boronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. This compound matters for its unique bifunctional structure, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected amine and fluorine substituents for further derivatization. It is primarily needed by pharmaceutical and agrochemical R&D teams for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as an organoboron partner for forming carbon-carbon bonds to create biaryl structures central to many bioactive compounds.
• Agrochemical Synthesis: Employed in the research and development of advanced pesticides and herbicides requiring specific fluorinated aromatic scaffolds.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries in medicinal chemistry campaigns.

Basic Information

Product Name	(3-(((2,4-Dimethoxybenzyl)Amino)Methyl)-5-Fluorophenyl)Boronic Acid
CAS No.	1704081-52-6
Molecular Formula	C₁₆H₁₉BFNO₄
Molecular Weight	319.14 g/mol
Synonyms	5-Fluoro-3-[[(2,4-dimethoxyphenyl)methylamino]methyl]benzeneboronic Acid; [3-[[(2,4-Dimethoxyphenyl)methylamino]methyl]-5-fluorophenyl]boronic Acid; B-(3-(((2,4-Dimethoxybenzyl)Amino)Methyl)-5-Fluorophenyl)boronic Acid; (3-(((2,4-Dimethoxybenzyl)Amino)Methyl)-5-Fluorophenyl)boronic Acid; 1704081-52-6; (3-(((2,4-Dimethoxybenzyl)Amino)Methyl)-5-Fluorophenyl)-Boronic Acid
EINECS	Contact for details

Quality Control

Our (3-(((2,4-Dimethoxybenzyl)Amino)Methyl)-5-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic (moisture-sensitive) nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.