Description

(3-Amino-4-Fluorophenyl)Boronic Acid Hydrochloride is a high-value, multifunctional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in oncology, CNS, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a precursor for organic electronic materials, including OLEDs, OFETs, and conductive polymers.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands for transition metal catalysis and sensing applications.
• Chemical Biology & Proteomics: Utilized in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors.
• Academic & Contract Research: Fundamental reagent for methodological development in cross-coupling and C-H functionalization chemistry.

Basic Information

Product Name	(3-Amino-4-Fluorophenyl)Boronic Acid Hydrochloride
CAS No.	1704081-06-0
Molecular Formula	C6H8BClFNO2
Molecular Weight	191.40 g/mol
Synonyms	3-Amino-4-fluorobenzeneboronic acid hydrochloride; 4-Fluoro-3-aminophenylboronic acid HCl; (4-Fluoro-3-aminophenyl)boronic acid hydrochloride; B-(3-Amino-4-fluorophenyl)boronic acid hydrochloride; 3-Amino-4-fluorophenylboronic acid HCl salt; AFPHBA-HCl; 1704081-06-0
EINECS	Contact for details

Quality Control

Every batch of our (3-Amino-4-Fluorophenyl)Boronic Acid Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity (typically >97% by HPLC), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light may affect purity and reactivity. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.