Description

(4-(3-(Dimethylamino)Propoxy)-3-Fluorophenyl)Boronic Acid Hydrochloride is a high-value, functionalized boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via the versatile Suzuki-Miyaura cross-coupling reaction. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its fluorine and boronic acid functionalities.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for palladium-catalyzed cross-coupling reactions to create biaryl and heterobiaryl structures, a cornerstone of modern medicinal chemistry.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular engineering is required.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	(4-(3-(Dimethylamino)Propoxy)-3-Fluorophenyl)Boronic Acid Hydrochloride
CAS No.	1704080-71-6
Molecular Formula	C₁₃H₂₁BClFNO₃
Molecular Weight	313.57 g/mol
Synonyms	[4-[3-(Dimethylamino)propoxy]-3-fluorophenyl]boronic acid hydrochloride; 3-Fluoro-4-[3-(dimethylamino)propoxy]benzeneboronic acid hydrochloride; (3-Fluoro-4-(3-(dimethylamino)propoxy)phenyl)boronic acid HCl; Boronic acid, B-[4-[3-(dimethylamino)propoxy]-3-fluorophenyl]-, hydrochloride; 1704080-71-6; CAS 1704080-71-6
EINECS	Contact for details

Quality Control

Every batch of (4-(3-(Dimethylamino)Propoxy)-3-Fluorophenyl)Boronic Acid Hydrochloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our products are developed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0%
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.