Description

(6-Bromo-2,3-Difluoro-4-Methoxyphenyl)Boronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the difluoro and bromo substituents for bioactivity.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and OFETs, where its structure aids in tuning electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organoboron catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs and fine chemical suppliers offering bespoke synthesis services to global clients.

Basic Information

Product Name	(6-Bromo-2,3-Difluoro-4-Methoxyphenyl)Boronic Acid
CAS No.	1704080-27-2
Molecular Formula	C7H6BBrF2O3
Molecular Weight	266.84 g/mol
Synonyms	(6-Bromo-2,3-difluoro-4-methoxyphenyl)boronic acid; 2-Bromo-3,4-difluoro-5-methoxybenzeneboronic acid; Boronic acid, B-(6-bromo-2,3-difluoro-4-methoxyphenyl)-; 6-Bromo-2,3-difluoro-4-methoxybenzeneboronic acid; (6-Bromo-2,3-difluoro-4-methoxyphenyl)boronic acid pinacol ester (common precursor); B-(6-Bromo-2,3-difluoro-4-methoxyphenyl)boronic acid; CAS 1704080-27-2
EINECS	Contact for details

Quality Control

Our (6-Bromo-2,3-Difluoro-4-Methoxyphenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.