Description

3-(4-Ethylpiperazine-1-Carbonyl)-4-Fluoro Phenyl Boronic Acid is a high-value, organoboron building block designed for advanced synthetic chemistry. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to synthesize novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, enabling the creation of complex molecular architectures with specific biological activity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, or organic electronic materials through palladium-catalyzed coupling reactions.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
• Process Chemistry & Scale-up: Provides a reliable and efficient coupling partner for optimizing synthetic routes from laboratory scale to pilot plant and commercial production.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and proprietary intermediates for clients.

Basic Information

Product Name	3-(4-Ethylpiperazine-1-Carbonyl)-4-Fluoro Phenyl Boronic Acid
CAS No.	1704074-46-3
Molecular Formula	C13H18BFN2O3
Molecular Weight	280.11 g/mol
Synonyms	4-Fluoro-3-[(4-ethylpiperazin-1-yl)carbonyl]benzeneboronic acid; (4-Fluoro-3-((4-ethylpiperazine-1-carbonyl)phenyl)boronic acid; 3-(4-Ethylpiperazine-1-carbonyl)-4-fluorobenzeneboronic acid; B-[4-Fluoro-3-[(4-ethyl-1-piperazinyl)carbonyl]phenyl]boronic acid; 1704074-46-3; 4-Fluoro-3-(4-ethylpiperazine-1-carbonyl)phenylboronic acid; AKOS026710293; FT-0777927
EINECS	Contact for details

Quality Control

Our production of 3-(4-Ethylpiperazine-1-Carbonyl)-4-Fluoro Phenyl Boronic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.