Description

(3-Fluoro-5-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique boronic acid functional group on a fluorinated aromatic scaffold. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between its aryl group and various aryl/vinyl halides or triflates under palladium catalysis.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: Utilized to create molecules for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for bespoke synthesis projects.

Basic Information

Product Name	(3-Fluoro-5-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid
CAS No.	1704074-44-1
Molecular Formula	C12H17BFNO2
Molecular Weight	237.08 g/mol
Synonyms	[3-Fluoro-5-(4-methyl-1-piperidinyl)phenyl]boronic acid; (3-Fluoro-5-(4-methylpiperidin-1-yl)phenyl)boronic acid; B-[3-Fluoro-5-(4-methyl-1-piperidinyl)phenyl]boronic acid; 3-Fluoro-5-(4-methylpiperidin-1-yl)benzeneboronic acid; 1-(3-Borono-5-fluorophenyl)-4-methylpiperidine; 1704074-44-1; Boronic acid, B-[3-fluoro-5-(4-methyl-1-piperidinyl)phenyl]-; AKOS026713293
EINECS	Contact for details

Quality Control

Our (3-Fluoro-5-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.