Description

4-(4-Ethylpiperazine-1-Carbonyl)-3-Fluorophenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a piperazine-carbonyl moiety that introduces key pharmacophoric elements. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine moiety.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to attach complex aryl groups in medicinal chemistry and materials science research.
• Agrochemical Research: Used in developing new active ingredients for crop protection with potential fungicidal or herbicidal activity.
• Chemical Biology Probe Synthesis: Facilitates the creation of labeled compounds and molecular probes for studying biological pathways and protein interactions.
• Ligand for Catalyst Development: The boronic acid group can be utilized to create novel ligands for transition metal catalysis.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries in drug discovery programs.

Basic Information

Product Name	4-(4-Ethylpiperazine-1-Carbonyl)-3-Fluorophenylboronic Acid
CAS No.	1704073-51-7
Molecular Formula	C13H18BFN2O3
Molecular Weight	280.11 g/mol
Synonyms	[3-Fluoro-4-[(4-ethyl-1-piperazinyl)carbonyl]phenyl]boronic acid; 4-(4-Ethylpiperazine-1-carbonyl)-3-fluorobenzeneboronic acid; 3-Fluoro-4-(4-ethylpiperazine-1-carbonyl)phenylboronic acid; Boronic acid, B-[3-fluoro-4-[(4-ethyl-1-piperazinyl)carbonyl]phenyl]-; 1704073-51-7; 4-(4-Ethylpiperazine-1-carbonyl)-3-fluorophenyl-B(OH)2; 3-Fluoro-4-(N-ethylpiperazine-1-carboxamide)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-(4-Ethylpiperazine-1-Carbonyl)-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.