Description

(4-Fluoro-3-(Pyrrolidin-1-Yl)Phenyl)Boronic Acid is a sophisticated aryl boronic acid derivative, a key building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, especially in medicinal chemistry programs targeting CNS and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its ability to form carbon-carbon bonds in complex heterocyclic systems.
• Material Science Research: Serves as a precursor for creating organic electronic materials, metal-organic frameworks (MOFs), and advanced polymers with tailored properties.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a versatile boronic acid coupling partner for the palladium-catalyzed formation of biaryl and other C-C bonds under mild conditions.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands for catalysis and molecular recognition applications.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes for studying biological systems.

Basic Information

Product Name	(4-Fluoro-3-(Pyrrolidin-1-Yl)Phenyl)Boronic Acid
CAS No.	1704073-15-3
Molecular Formula	C10H13BFNO2
Molecular Weight	209.03 g/mol
Synonyms	[4-Fluoro-3-(1-Pyrrolidinyl)phenyl]boronic Acid; (4-Fluoro-3-pyrrolidin-1-ylphenyl)boronic Acid; B-[4-Fluoro-3-(1-Pyrrolidinyl)phenyl]boronic Acid; 3-Pyrrolidin-1-yl-4-fluorophenylboronic Acid; 4-Fluoro-3-pyrrolidin-1-ylbenzeneboronic Acid; 1704073-15-3; Boronic acid, B-[4-fluoro-3-(1-pyrrolidinyl)phenyl]-; AKOS026712293
EINECS	Contact for details

Quality Control

Our (4-Fluoro-3-(Pyrrolidin-1-Yl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.