Description

(3-Morpholino-5-(Trifluoromethyl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of the morpholine ring, which can modulate solubility and pharmacokinetic properties, and the trifluoromethyl group, known for enhancing metabolic stability and lipophilicity. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex molecules via Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to biological activity.
• Material Science Research: Employed in the creation of novel organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: Primarily utilized as an organoboron reagent in palladium-catalyzed cross-coupling reactions to form biaryl and heterobiaryl structures, a cornerstone of modern C-C bond formation.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the development of molecular probes for diagnostic and research applications.

Basic Information

Product Name	(3-Morpholino-5-(Trifluoromethyl)Phenyl)Boronic Acid
CAS No.	1704069-70-4
Molecular Formula	C11H13BF3NO3
Molecular Weight	275.04 g/mol
Synonyms	5-(Trifluoromethyl)-3-morpholinophenylboronic acid; 3-Morpholino-5-(trifluoromethyl)benzeneboronic acid; [3-Morpholino-5-(trifluoromethyl)phenyl]boronic acid; Boronic acid, B-[3-morpholino-5-(trifluoromethyl)phenyl]-; 3-Morpholino-5-trifluoromethylphenylboronic acid; (3-Morpholin-5-(trifluoromethyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our (3-Morpholino-5-(Trifluoromethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing the specific results for each lot are available upon request. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.