Description

(2,3-Difluoro-4-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative and a key building block in modern synthetic chemistry. Its value lies in its role as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials. The compound, CAS 1704069-62-4, is supplied with a focus on batch-to-batch consistency and reliable reactivity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Agrochemical Research: Used to construct complex molecular scaffolds for the development of new herbicides, fungicides, and insecticides.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as those used in OLEDs and semiconductors.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boron reagent for palladium-catalyzed C-C bond formation to create complex, functionalized biaryl compounds.
• Ligand Synthesis: Can be utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	(2,3-Difluoro-4-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid
CAS No.	1704069-62-4
Molecular Formula	C12H16BF2NO2
Molecular Weight	255.07 g/mol
Synonyms	[2,3-Difluoro-4-(4-methyl-1-piperidinyl)phenyl]boronic acid; (2,3-Difluoro-4-(4-methylpiperidin-1-yl)phenyl)boronic acid; 4-(4-Methylpiperidin-1-yl)-2,3-difluorophenylboronic acid; B-[2,3-Difluoro-4-(4-methyl-1-piperidinyl)phenyl]boronic acid; 2,3-Difluoro-4-(4-methylpiperidin-1-yl)benzeneboronic acid; PINAP Boronic Acid Derivative (contextual); 1-(2,3-Difluoro-4-boronophenyl)-4-methylpiperidine
EINECS	Contact for details

Quality Control

Our (2,3-Difluoro-4-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.