Description

(3-(4-Methylpiperidin-1-Yl)-5-(Trifluoromethyl)Phenyl)Boronic Acid is a high-value, synthetically versatile organoboron compound. It serves as a critical building block in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and functional materials. Its unique structure, featuring both a trifluoromethyl group and a piperidine moiety, offers distinct advantages in modulating the physicochemical properties of target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in CNS and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of activity-based probes for target identification.
• Catalyst Ligand Development: The boronic acid and heterocyclic amine functionalities make it a candidate for designing novel ligands in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	(3-(4-Methylpiperidin-1-Yl)-5-(Trifluoromethyl)Phenyl)Boronic Acid
CAS No.	1704068-89-2
Molecular Formula	C13H17BF3NO2
Molecular Weight	287.09 g/mol
Synonyms	[3-(4-Methyl-1-piperidinyl)-5-(trifluoromethyl)phenyl]boronic acid; 3-(4-Methylpiperidin-1-yl)-5-(trifluoromethyl)benzeneboronic acid; 1-[3-Borono-5-(trifluoromethyl)phenyl]-4-methylpiperidine; (3-(4-Methylpiperidin-1-yl)-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[3-(4-methyl-1-piperidinyl)-5-(trifluoromethyl)phenyl]-; 1704068-89-2; AKOS026713023
EINECS	Contact for details

Quality Control

Our (3-(4-Methylpiperidin-1-Yl)-5-(Trifluoromethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.