Description

(3-(4-Ethylpiperazin-1-Yl)-5-(Trifluoromethyl)Phenyl)Boronic Acid is a high-value, organoboron building block featuring a trifluoromethyl group and an ethylpiperazine moiety. This compound is essential for modern synthetic chemistry, enabling the precise construction of complex molecules through reliable cross-coupling reactions. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Serves as a precursor for creating advanced organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) agents to study enzyme function.
• Ligand Synthesis: Useful for constructing complex ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring this specialized boronic acid derivative.

Basic Information

Product Name	(3-(4-Ethylpiperazin-1-Yl)-5-(Trifluoromethyl)Phenyl)Boronic Acid
CAS No.	1704068-77-8
Molecular Formula	C13H18BF3N2O2
Molecular Weight	302.11 g/mol
Synonyms	[3-(4-Ethyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]boronic acid; Boronic acid, B-[3-(4-ethyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]-; (3-(4-Ethylpiperazin-1-yl)-5-(trifluoromethyl)phenyl)boronic acid; 3-(4-Ethylpiperazin-1-yl)-5-(trifluoromethyl)benzeneboronic acid; 1704068-77-8; AKOS026713293; FT-0774141; A937091
EINECS	Contact for details

Quality Control

Every batch of (3-(4-Ethylpiperazin-1-Yl)-5-(Trifluoromethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive R&D and scale-up applications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically >95% by HPLC), and impurity profile is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.