Description

(4,5-Difluoro-2-((4-Methylpiperazin-1-yl)sulfonyl)phenyl)boronic acid is a sophisticated boronic acid derivative featuring a sulfonylpiperazine substituent, making it a valuable building block for modern synthetic chemistry. This compound is specifically engineered for applications requiring precise molecular coupling, offering high reactivity and selectivity in cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Agrochemical Research: Used in the discovery and development of new herbicides and fungicides with enhanced efficacy.
• Material Science: Serves as a monomer or functionalization agent in creating novel polymers and organic electronic materials.
• Chemical Biology: Employed in the synthesis of probes and ligands for studying biological targets and pathways.
• Catalyst Development: Acts as a ligand or co-catalyst in designing new catalytic systems for organic transformations.
• Custom Synthesis: Provides a versatile handle for medicinal chemists to introduce specific fluorinated, sulfonated, and boronic acid functionalities into target molecules.

Basic Information

Product Name	(4,5-Difluoro-2-((4-Methylpiperazin-1-yl)sulfonyl)phenyl)boronic Acid
CAS No.	1704067-49-1
Molecular Formula	C11H15BF2N2O4S
Molecular Weight	328.12 g/mol
Synonyms	[4,5-Difluoro-2-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]boronic acid; 2-[(4-Methylpiperazin-1-yl)sulfonyl]-4,5-difluorophenylboronic acid; 4,5-Difluoro-2-((4-methylpiperazin-1-yl)sulfonyl)benzeneboronic acid; B-[4,5-Difluoro-2-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]boronic acid; 1704067-49-1; Boronic acid, B-[4,5-difluoro-2-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-; AKOS026713095
EINECS	Contact for details

Quality Control

Our (4,5-Difluoro-2-((4-Methylpiperazin-1-yl)sulfonyl)phenyl)boronic acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC), identity confirmation (by NMR and IR), and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.