Description

(3,4-Difluoro-5-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid is a sophisticated organoboron compound, specifically a boronic acid derivative, that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the presence of the 4-methylpiperidine moiety.
• Agrochemical Research: Used in creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Employed in the development of organic electronic materials, such as those for OLEDs and semiconductors, via polymerization or functionalization.
• Suzuki-Miyaura Cross-Coupling: Serves as a pivotal boronic acid reagent for forming carbon-carbon bonds between aromatic rings under mild conditions.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and sensors that leverage boronic acid's affinity for diols.
• Ligand Synthesis: Acts as a starting material for creating novel ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	(3,4-Difluoro-5-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid
CAS No.	1704067-16-2
Molecular Formula	C12H16BF2NO2
Molecular Weight	255.07 g/mol
Synonyms	[3,4-Difluoro-5-(4-methyl-1-piperidinyl)phenyl]boronic acid; 5-(4-Methylpiperidin-1-yl)-3,4-difluorophenylboronic acid; (3,4-Difluoro-5-(4-methylpiperidin-1-yl)phenyl)boronic acid; Boronic acid, B-[3,4-difluoro-5-(4-methyl-1-piperidinyl)phenyl]-; 1704067-16-2; 3,4-Difluoro-5-(4-methylpiperidin-1-yl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our (3,4-Difluoro-5-(4-Methylpiperidin-1-Yl)Phenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.