Description

4-Fluoro-3-((2,2,2-Trifluoroethoxy)Methyl)Phenylboronic Acid is a sophisticated organoboron building block, specifically a fluorinated phenylboronic acid derivative, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This high-purity intermediate is critically needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides where the introduction of fluorine and trifluoroethoxy groups enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other transition metal-catalyzed processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where fluorinated aromatic systems are advantageous.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) engaged in custom synthesis projects for clients.

Basic Information

Product Name	4-Fluoro-3-((2,2,2-Trifluoroethoxy)Methyl)Phenylboronic Acid
CAS No.	1704067-12-8
Molecular Formula	C9H9BF4O3
Molecular Weight	252.0 g/mol (approx.)
Synonyms	[4-Fluoro-3-[(2,2,2-trifluoroethoxy)methyl]phenyl]boronic acid; (4-Fluoro-3-((2,2,2-trifluoroethoxy)methyl)phenyl)boronic acid; 4-Fluoro-3-(2,2,2-trifluoroethoxymethyl)benzeneboronic acid; 3-(Trifluoroethoxymethyl)-4-fluorophenylboronic acid; Boronic acid, B-[4-fluoro-3-[(2,2,2-trifluoroethoxy)methyl]phenyl]-; 1704067-12-8
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-((2,2,2-Trifluoroethoxy)Methyl)Phenylboronic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.