Description

(2-(N,n-Diethylsulfamoyl)-4,5-Difluorophenyl)Boronic Acid is a high-purity, functionalized boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to create novel, complex molecules. Its unique structure, featuring a diethylsulfamoyl group and difluoro substitution, offers specific reactivity and selectivity advantages for challenging synthetic targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymeric materials, including sensors and organic electronic components.
• Chemical Biology & Probe Development: Employed in the creation of chemical probes and bioconjugates for studying biological pathways and protein interactions.
• Catalyst Ligand Synthesis: Acts as a starting material for synthesizing sophisticated ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	(2-(N,n-Diethylsulfamoyl)-4,5-Difluorophenyl)Boronic Acid
CAS No.	1704066-89-6
Molecular Formula	C10H14BF2NO4S
Molecular Weight	289.10 g/mol
Synonyms	2-(N,N-Diethylsulfamoyl)-4,5-difluorophenylboronic acid; [2-(Diethylsulfamoyl)-4,5-difluorophenyl]boronic acid; 4,5-Difluoro-2-(N,N-diethylsulfamoyl)benzeneboronic acid; Boronic acid, B-[2-[(diethylamino)sulfonyl]-4,5-difluorophenyl]-; B-[2-(Diethylsulfamoyl)-4,5-difluorophenyl]boronic acid; 1704066-89-6; (2-Diethylsulfamoyl-4,5-difluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our (2-(N,n-Diethylsulfamoyl)-4,5-Difluorophenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; therefore, it is recommended to store under an inert atmosphere (argon or nitrogen) and handle in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.