Description

(3-Fluoro-5-(Morpholinomethyl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a morpholine-substituted benzyl group, making it a valuable building block in modern synthetic chemistry. This compound is specifically engineered for use in cross-coupling reactions, most notably the Suzuki-Miyaura reaction, to construct complex molecular architectures. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in materials science for creating advanced organic electronic components.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in creating biaryl structures common in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific fluorinated aromatic motifs.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its functional boronic acid group and aromatic core.
• Chemical Biology & Probe Development: Serves as a precursor for creating fluorescent probes or affinity tags that target specific proteins or biological pathways.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds between aromatic rings efficiently and under mild conditions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in methodological development and complex molecule synthesis.

Basic Information

Product Name	(3-Fluoro-5-(Morpholinomethyl)Phenyl)Boronic Acid
CAS No.	1704066-79-4
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	[3-Fluoro-5-(morpholin-4-ylmethyl)phenyl]boronic acid; (3-Fluoro-5-(4-morpholinylmethyl)phenyl)boronic acid; B-[3-Fluoro-5-(morpholinomethyl)phenyl]boronic acid; 3-Fluoro-5-(morpholinomethyl)benzeneboronic acid; 5-(Morpholinomethyl)-3-fluorobenzeneboronic acid; 1704066-79-4; Boronic acid, B-[3-fluoro-5-(4-morpholinylmethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our (3-Fluoro-5-(Morpholinomethyl)Phenyl)Boronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.