Description

(2-(N,n-Dimethylsulfamoyl)-4,5-Difluorophenyl)Boronic Acid is a sophisticated organoboron compound featuring a unique difluorophenyl core modified with a dimethylsulfamoyl group. This structure makes it a highly valuable specialty building block for advanced chemical synthesis, particularly in the development of complex molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the fluorine atoms for enhanced metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Catalyst Ligand Development: The boronic acid and sulfonamide functionalities make it a candidate for developing novel ligands in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(2-(N,n-Dimethylsulfamoyl)-4,5-Difluorophenyl)Boronic Acid
CAS No.	1704065-67-7
Molecular Formula	C8H10BF2NO4S
Molecular Weight	277.04 g/mol
Synonyms	(2-(Dimethylsulfamoyl)-4,5-difluorophenyl)boronic acid; 4,5-Difluoro-2-(N,N-dimethylsulfamoyl)phenylboronic acid; B-[2-(Dimethylsulfamoyl)-4,5-difluorophenyl]boronic acid; 2-(N,N-Dimethylsulfamoyl)-4,5-difluorobenzeneboronic acid; (2-(Dimethylsulfamoyl)-4,5-difluorophenyl)boronic acid pinacol ester (common derivative); CAS 1704065-67-7; Boronic acid, B-[2-(dimethylsulfamoyl)-4,5-difluorophenyl]- (IUPAC)
EINECS	Contact for details

Quality Control

Our production of (2-(N,n-Dimethylsulfamoyl)-4,5-Difluorophenyl)Boronic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.