Description

(3-(Morpholinosulfonyl)-4-(Trifluoromethoxy)Phenyl)Boronic Acid is a sophisticated organoboron building block designed for advanced synthetic chemistry. This compound matters for its unique trifluoromethoxy and morpholinosulfonyl substituents, which are critical for modulating the physicochemical properties of target molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymeric materials, including sensors and organic electronic components.
• Suzuki-Miyaura Cross-Coupling: Primarily employed in palladium-catalyzed cross-coupling reactions to form biaryl and heterobiaryl structures, a cornerstone of modern medicinal chemistry.
• Chemical Biology Probe Development: Utilized in creating molecular probes and tags for studying biological processes and target engagement.
• Ligand Synthesis for Catalysis: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	(3-(Morpholinosulfonyl)-4-(Trifluoromethoxy)Phenyl)Boronic Acid
CAS No.	1704065-47-3
Molecular Formula	C11H13BF3NO5S
Molecular Weight	339.10 g/mol
Synonyms	[3-(Morpholine-4-sulfonyl)-4-(trifluoromethoxy)phenyl]boronic acid; 4-(Trifluoromethoxy)-3-(morpholinosulfonyl)benzeneboronic acid; 3-Morpholinosulfonyl-4-trifluoromethoxybenzeneboronic acid; Boronic acid, B-[3-(4-morpholinosulfonyl)-4-(trifluoromethoxy)phenyl]-; (3-Morpholinosulfonyl-4-trifluoromethoxyphenyl)boronic acid; 1704065-47-3; CAS 1704065-47-3
EINECS	Contact for details

Quality Control

Our (3-(Morpholinosulfonyl)-4-(Trifluoromethoxy)Phenyl)Boronic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP standards for pharmaceutical-grade material upon demand.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.