Description

(4-((4-Ethylpiperazin-1-yl)Methyl)-2-Fluorophenyl)Boronic Acid is a high-value boronic acid derivative featuring a piperazine and fluorophenyl scaffold. This compound is a critical advanced pharmaceutical intermediate and Suzuki-Miyaura cross-coupling reagent used in the synthesis of complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct novel chemical entities and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds between aromatic rings, enabling the construction of complex biaryl structures in drug discovery and material science.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific fluorinated and nitrogen-containing motifs.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials in advanced display technologies.
• Ligand Synthesis for Catalysis: Building block for creating novel ligands used in homogeneous catalysis and asymmetric synthesis.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Used in the design and synthesis of bifunctional molecules for targeted protein degradation.

Basic Information

Product Name	(4-((4-Ethylpiperazin-1-yl)Methyl)-2-Fluorophenyl)Boronic Acid
CAS No.	1704064-26-5
Molecular Formula	C13H20BFN2O2
Molecular Weight	266.12 g/mol
Synonyms	2-Fluoro-4-[(4-ethylpiperazin-1-yl)methyl]benzeneboronic acid; [4-[(4-Ethyl-1-piperazinyl)methyl]-2-fluorophenyl]boronic acid; 4-[(4-Ethylpiperazin-1-yl)methyl]-2-fluorobenzeneboronic acid; 1704064-26-5; B-[4-[(4-Ethyl-1-piperazinyl)methyl]-2-fluorophenyl]boronic acid
EINECS	Contact for details

Quality Control

Our (4-((4-Ethylpiperazin-1-yl)Methyl)-2-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.