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(2-Fluoro-4-((4-Methylpiperazin-1-Yl)Methyl)Phenyl)Boronic Acid CAS NO 1704064-24-3


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CAS No.:1704064-24-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2-Fluoro-4-((4-Methylpiperazin-1-yl)Methyl)Phenyl)Boronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for applications in medicinal chemistry and drug discovery.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
  • Medicinal Chemistry Research: Used extensively in drug discovery for the construction of compound libraries and structure-activity relationship (SAR) studies.
  • Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
  • Material Science: Potential use in the synthesis of advanced organic materials, such as organic light-emitting diodes (OLEDs) and polymers.
  • Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and other carbon-carbon bonds with high selectivity.
  • Chemical Biology Probes: Can be employed in the development of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name (2-Fluoro-4-((4-Methylpiperazin-1-yl)Methyl)Phenyl)Boronic Acid
CAS No. 1704064-24-3
Molecular Formula C12H18BFN2O2
Molecular Weight 252.10 g/mol
Synonyms [2-Fluoro-4-[(4-methylpiperazin-1-yl)methyl]phenyl]boronic acid; 2-Fluoro-4-((4-methylpiperazin-1-yl)methyl)benzeneboronic acid; 4-(4-Methylpiperazin-1-ylmethyl)-2-fluorophenylboronic acid; Boronic acid, B-[2-fluoro-4-[(4-methyl-1-piperazinyl)methyl]phenyl]-; 1704064-24-3; (2-Fluoro-4-((4-methylpiperazin-1-yl)methyl)phenyl)boronic acid pinacol ester (common protected form)
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Quality Control

Our (2-Fluoro-4-((4-Methylpiperazin-1-yl)Methyl)Phenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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