Description

(2-Fluoro-4-((4-Oxopiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is a high-purity boronic acid derivative featuring a piperidinone moiety, serving as a critical advanced pharmaceutical intermediate and building block in modern synthetic chemistry. Its molecular architecture makes it indispensable for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds between aryl halides and boronic acids, enabling the construction of complex, drug-like molecules.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential monomer or precursor for advanced organic electronic materials and polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D and scale-up activities.

Basic Information

Product Name	(2-Fluoro-4-((4-Oxopiperidin-1-Yl)Methyl)Phenyl)Boronic Acid
CAS No.	1704064-22-1
Molecular Formula	C13H17BFNO3
Molecular Weight	265.09 g/mol
Synonyms	1-(4-(2-Fluorophenyl)-2-borono-benzyl)piperidin-4-one; [2-Fluoro-4-(4-oxo-1-piperidinylmethyl)phenyl]boronic acid; (2-Fluoro-4-((4-oxopiperidin-1-yl)methyl)phenyl)boronic acid; B-[2-Fluoro-4-[(4-oxo-1-piperidinyl)methyl]phenyl]boronic acid; 4-(2-Fluoro-4-boronobenzyl)piperidin-4-one; 1704064-22-1; Boronic acid, B-[2-fluoro-4-[(4-oxo-1-piperidinyl)methyl]phenyl]-; AKOS026712293
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-((4-Oxopiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.