Description

(3-Fluoro-5-((4-Oxopiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is a high-purity, advanced pharmaceutical intermediate featuring a boronic acid functional group integrated with a piperidinone scaffold. This compound is of significant value for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in oncology, CNS, and metabolic disease research.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds between aryl halides and boronic acids, enabling the construction of complex, drug-like molecules.
• Medicinal Chemistry Research: Employed in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve compound properties.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to outsourcing partners for custom synthesis and scale-up projects under cGMP or research-grade conditions.

Basic Information

Product Name	(3-Fluoro-5-((4-Oxopiperidin-1-Yl)Methyl)Phenyl)Boronic Acid
CAS No.	1704063-68-2
Molecular Formula	C12H15BFNO3
Molecular Weight	251.07 g/mol
Synonyms	1-(3-Fluoro-5-(boronomethyl)benzyl)piperidin-4-one; [3-Fluoro-5-[(4-oxo-1-piperidyl)methyl]phenyl]boronic acid; (3-Fluoro-5-(piperidin-4-on-1-ylmethyl)phenyl)boronic acid; B-[3-Fluoro-5-[(4-oxo-1-piperidinyl)methyl]phenyl]boronic acid; 1704063-68-2; Boronic acid, B-[3-fluoro-5-[(4-oxo-1-piperidinyl)methyl]phenyl]-; AKOS026713293
EINECS	Contact for details

Quality Control

Our (3-Fluoro-5-((4-Oxopiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with research-grade or cGMP standards based on customer project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.