Description

4-Fluoro-3-Methoxy-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative used as a key synthetic building block. Its molecular structure, featuring both fluorine and methoxy substituents, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for creating specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for catalysis and molecular recognition applications.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Fluoro-3-Methoxy-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1701449-45-7
Molecular Formula	C9H7BF4O3
Molecular Weight	250.96 g/mol
Synonyms	[4-Fluoro-3-methoxy-5-(trifluoromethyl)phenyl]boronic acid; (4-Fluoro-3-methoxy-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[4-fluoro-3-methoxy-5-(trifluoromethyl)phenyl]-; 4-Fluoro-3-methoxy-5-trifluoromethylbenzeneboronic acid; 5-Trifluoromethyl-4-fluoro-3-methoxyphenylboronic acid; CAS 1701449-45-7
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methoxy-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.