Description

Tyrosine, n-[(1,1-Dimethylethoxy)Carbonyl]-3,5-Dimethyl- is a protected tyrosine derivative, specifically a Boc-protected dimethyltyrosine analog, designed for advanced peptide synthesis and pharmaceutical research. This compound is critical for enabling complex chemical transformations by safeguarding reactive functional groups during multi-step synthetic sequences. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel therapeutic peptides and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Peptide Research: Used in academic and industrial R&D for constructing peptides with specific structural motifs, particularly those requiring protection of the phenolic hydroxyl group.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for peptide drugs, where the Boc protecting group offers orthogonal deprotection strategies.
• Bioconjugation: Serves as a precursor for creating modified amino acids used in antibody-drug conjugates (ADCs) and other bioconjugation platforms.
• Chemical Biology Probes: Integral for synthesizing labeled or tagged peptide probes used to study protein-protein interactions and enzyme function.

Basic Information

Product Name	Tyrosine, n-[(1,1-Dimethylethoxy)Carbonyl]-3,5-Dimethyl-
CAS No.	1700567-31-2
Molecular Formula	C16H23NO5
Molecular Weight	309.36 g/mol
Synonyms	Boc-3,5-Dimethyl-L-tyrosine; N-Boc-3,5-Dimethyltyrosine; tert-Butyloxycarbonyl-3,5-dimethyl-L-tyrosine; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,5-dimethyl-4-hydroxyphenyl)propanoic acid; Boc-Dmt-OH; Boc-3,5-Dimethyl-Tyr-OH; N-(tert-Butoxycarbonyl)-3,5-dimethyl-L-tyrosine
EINECS	Contact for details

Quality Control

Our Tyrosine, n-[(1,1-Dimethylethoxy)Carbonyl]-3,5-Dimethyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure traceability and batch-to-batch consistency, meeting the stringent requirements of research and cGMP-grade production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.