Description

3-Fluoro-4'-Methyl[1,1']Biphenyl-4-Yl-Boronic Acid is a high-purity, synthetically valuable boronic acid derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation, which is essential for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as drug discovery and the synthesis of functional organic compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and conjugated systems central to active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those requiring fluoro- and methyl-substituted biphenyl scaffolds.
• Agrochemical Research: Employed in the synthesis of advanced herbicides, fungicides, and insecticides that leverage the stability and reactivity of the biphenyl core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science: A building block for organic semiconductors, liquid crystals, and polymers where specific fluorine substitution patterns are required to tune electronic properties.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	3-Fluoro-4'-Methyl[1,1']Biphenyl-4-Yl-Boronic Acid
CAS No.	1698890-39-9
Molecular Formula	C14H14BFO2
Molecular Weight	244.07 g/mol
Synonyms	4-(3-Fluoro-4'-methyl-[1,1'-biphenyl]-4-yl)boronic acid; [1,1'-Biphenyl]-4-boronic acid, 3-fluoro-4'-methyl-; 3-Fluoro-4'-methylbiphenyl-4-boronic acid; (3-Fluoro-4'-methyl[1,1'-biphenyl]-4-yl)boronic acid; 4-Borono-3-fluoro-4'-methyl-1,1'-biphenyl; 3-Fluoro-4'-methyl-1,1'-biphenyl-4-boronic acid; 3-Fluoro-4'-methylbiphenyl-4-ylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4'-Methyl[1,1']Biphenyl-4-Yl-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.