Description

2，2-Difluoro-2-(3-Methoxypyridin-2-Yl)Acetic Acid is a high-purity fluorinated pyridine derivative serving as a critical synthetic intermediate. Its value lies in enabling the precise construction of complex molecules, particularly in advanced pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the stability imparted by the difluoroacetic acid moiety.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: A valuable reagent for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Material Science Precursor: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials.

Basic Information

Product Name	2，2-Difluoro-2-(3-Methoxypyridin-2-Yl)Acetic Acid
CAS No.	1698403-23-4
Molecular Formula	C9H7F2NO3
Molecular Weight	215.15 g/mol
Synonyms	2-(3-Methoxypyridin-2-yl)-2,2-difluoroacetic acid; α,α-Difluoro-2-(3-methoxy-2-pyridinyl)acetic Acid; 2,2-Difluoro-2-(3-methoxypyridin-2-yl)ethanoic Acid; 3-Methoxy-2-pyridinyldifluoroacetic Acid; 1698403-23-4; DFMPA; Difluoro(3-methoxy-2-pyridinyl)acetic Acid
EINECS	Contact for details

Quality Control

Every batch of 2，2-Difluoro-2-(3-Methoxypyridin-2-Yl)Acetic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.