Description

3-(Bromomethyl)-1,1-Difluorocyclopentane is a versatile fluorinated cyclopentane derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its unique combination of a reactive bromomethyl handle and the stability-modifying difluoromethylene group, enabling precise molecular construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for introducing the cyclopentyl-difluoromethylene pharmacophore into drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides where the difluoro group can influence biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a fluorinated core component for synthesizing advanced electronic and display materials.
• Polymer Modification: Employed to incorporate fluorine into polymer backbones or side chains, altering properties like chemical resistance, surface energy, and thermal stability.
• Cross-coupling Reactions: The bromomethyl group acts as a versatile handle for further functionalization via Suzuki, Negishi, or other metal-catalyzed cross-coupling methodologies.
• Probe & Sensor Development: Useful in medicinal chemistry and chemical biology for creating fluorescent probes or affinity labels targeting specific enzymes or receptors.

Basic Information

Item	Details
Product Name	3-(Bromomethyl)-1,1-Difluorocyclopentane
CAS No.	1695914-13-6
Molecular Formula	C7H11BrF2
Molecular Weight	213.06 g/mol
Synonyms	1,1-Difluoro-3-(bromomethyl)cyclopentane; 3-Bromomethyl-1,1-difluorocyclopentane; (Bromomethyl)difluorocyclopentane; Cyclopentane, 3-(bromomethyl)-1,1-difluoro-; 1,1-Difluorocyclopentane-3-methyl bromide
EINECS	Contact for details

Quality Control

Our 3-(Bromomethyl)-1,1-Difluorocyclopentane is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.