Description

2-Bromo-3-Fluoro-4-Hydroxybenzonitrile is a high-purity, multi-functional halogenated aromatic nitrile building block. This compound matters for its unique molecular architecture, combining bromine, fluorine, and a hydroxy group on a benzonitrile core, which is critical for introducing specific steric and electronic properties into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine and bromine substituents enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	2-Bromo-3-Fluoro-4-Hydroxybenzonitrile
CAS No.	1690654-52-4
Molecular Formula	C7H3BrFNO
Molecular Weight	216.01 g/mol
Synonyms	4-Hydroxy-2-bromo-3-fluorobenzonitrile; 2-Bromo-3-fluoro-4-hydroxybenzenecarbonitrile; Benzonitrile, 2-bromo-3-fluoro-4-hydroxy-; 1690654-52-4; 2-Br-3-F-4-OH-BnCN
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Fluoro-4-Hydroxybenzonitrile is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS, to ensure compliance with exacting customer specifications and industry standards. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.