Description

Remdesivir-003-R CAS NO 1689993-65-4 is a high-purity chemical intermediate, specifically a key building block in the synthesis of the antiviral prodrug Remdesivir. This compound is critical for ensuring the quality, consistency, and regulatory compliance of the final active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers, advanced research institutions, and fine chemical synthesis facilities engaged in the development and production of antiviral therapeutics.

Application

• Pharmaceutical Synthesis: A crucial intermediate in the multi-step synthesis of the antiviral drug Remdesivir (GS-5734).
• API Manufacturing: Used in the controlled production of the Remdesivir Active Pharmaceutical Ingredient (API) under Good Manufacturing Practice (GMP) conditions.
• Research & Development: Serves as a reference standard and a key precursor in medicinal chemistry research for novel nucleoside analogs and antiviral agents.
• Process Development: Employed in scaling up and optimizing synthetic routes for antiviral compounds within process chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of antiviral drug substances.

Basic Information

Product Name	Remdesivir-003-R
CAS No.	1689993-65-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GS-441524 Nucleoside Precursor; Remdesivir Intermediate-003-R; 2-Ethylbutyl (2S)-2-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate (IUPAC); GS-5734 Intermediate; Antiviral Nucleoside Analog Intermediate; Veklury® Synthesis Intermediate
EINECS	Contact for details

Quality Control

Our Remdesivir-003-R is manufactured under strict quality control protocols suitable for pharmaceutical applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for use in API synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to support regulatory filings and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.