Description

2-Chloro-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds.
• Pharmaceutical Intermediate: Used in the research and development of new active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl and halogenated aryl motifs.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and molecular probes for biological studies.

Basic Information

Product Name	2-Chloro-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	1689550-75-1
Molecular Formula	C₁₃H₁₅BClF₃O₂
Molecular Weight	306.52 g/mol
Synonyms	2-Chloro-3-(trifluoromethyl)benzeneboronic acid pinacol ester; (2-Chloro-3-(trifluoromethyl)phenyl)boronic acid pinacol ester; 2-Chloro-α,α,α-trifluoro-m-tolylboronic acid pinacol ester; 2-Chloro-3-trifluoromethylphenylboronic acid pinacol ester; Pinacol [2-chloro-3-(trifluoromethyl)phenyl]boronate; B-[2-Chloro-3-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed in a dry environment to prevent moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.