Description

2-Chloro-3-Fluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound matters as a critical building block in modern cross-coupling reactions, enabling the efficient and selective construction of complex molecules. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester derivative.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs) containing a substituted phenyl ring.
• Agrochemical Development: Serves as a building block for novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Used to create organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology & Probe Development: Facilitates the synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	2-Chloro-3-Fluorophenylboronic Acid Pinacol Ester
CAS No.	1688698-58-9
Molecular Formula	C12H15BClFO2
Molecular Weight	255.51 g/mol
Synonyms	2-Chloro-3-fluorobenzeneboronic acid pinacol ester; (2-Chloro-3-fluorophenyl)boronic acid pinacol ester; 2-Chloro-3-fluorophenylboronic acid neopentyl glycol ester (common alternative); 2-Chloro-3-fluoro-1,3,2-benzodioxaborole (tautomeric form); B-(2-Chloro-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-chloro-3-fluorophenyl)boronate; 2-Fluoro-6-chlorophenylboronic acid pinacol ester (isomer reference); CAS 1688698-58-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.