Description

2-Methoxy-5-(Trifluoromethyl)Phenylboronic Acidpinacol Ester CAS NO 1688686-12-5 is a high-purity, advanced pharmaceutical intermediate and versatile organoboron building block. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern medicinal chemistry for constructing complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl-substituted biaryl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the unique properties of the trifluoromethyl group.
• Material Science: Serves as a precursor for creating functionalized organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new C-C bond formation methodologies and creating diverse compound libraries.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	2-Methoxy-5-(Trifluoromethyl)Phenylboronic Acidpinacol Ester
CAS No.	1688686-12-5
Molecular Formula	C₁₄H₁₈BF₃O₃
Molecular Weight	302.10 g/mol
Synonyms	2-Methoxy-5-(trifluoromethyl)benzeneboronic acid pinacol ester; (2-Methoxy-5-(trifluoromethyl)phenyl)boronic acid pinacol ester; 2-Methoxy-α,α,α-trifluoro-p-tolylboronic acid pinacol ester; 5-(Trifluoromethyl)-2-methoxyphenylboronic acid pinacol ester; B-[2-Methoxy-5-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 2-Methoxy-5-(trifluoromethyl)phenylboronate
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-(Trifluoromethyl)Phenylboronic Acidpinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.