Description

n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-o-[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-β-D-Galactopyranosyl]-L-Serine is a sophisticated, protected amino acid-glycosyl conjugate, serving as a critical building block in advanced organic synthesis. This compound is essential for the controlled construction of complex glycopeptides and glycoproteins, enabling research into carbohydrate-protein interactions. It is primarily utilized by pharmaceutical R&D teams, medicinal chemists, and bioconjugation specialists working on next-generation therapeutics, including targeted cancer treatments and vaccine development.

Application

• Glycopeptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of O-linked glycopeptides, mimicking natural post-translational modifications.
• Pharmaceutical Research: Used in the development of novel biopharmaceuticals, including antibody-drug conjugates (ADCs) and therapeutic glycoproteins.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by providing a selectively protected serine derivative with a complex carbohydrate moiety.
• Bioconjugation: Serves as a specialized linker or spacer molecule for attaching carbohydrate epitopes to carrier proteins or other biomolecules.
• Carbohydrate Chemistry: A valuable substrate for studying glycosylation reactions and enzyme specificity due to its acetyl-protected galactosamine group.
• Probe and Diagnostic Development: Can be incorporated into fluorescent or affinity probes for studying lectin binding and cellular uptake mechanisms.

Basic Information

Product Name	n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-o-[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-β-D-Galactopyranosyl]-L-Serine
CAS No.	1676104-71-4
Molecular Formula	C34H38N2O13
Molecular Weight	682.67 g/mol
Synonyms	Fmoc-Ser(Ac3-β-D-GalNAc)-OH; Fmoc-O-(3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-L-serine; Fmoc-L-Ser[β-D-GalNAc(Ac)3]-OH; N-α-Fmoc-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-galactopyranosyl)-L-serine; Fmoc-Ser(GalNAc(Ac)3)-OH; Glycosylated Fmoc-Serine derivative; Protected Fmoc-serine galactosamine conjugate
EINECS	Contact for details

Quality Control

Every batch of our n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-o-[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-β-D-Galactopyranosyl]-L-Serine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research and process development. Certificates of Analysis (COA) detailing specifications from HPLC, NMR, and MS are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.