Description

Carbamic Acid, n-[(1R)-1-Cyano-2-(1,1-Dimethylethoxy)Ethyl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral carbamate derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the synthesis of novel therapeutic agents and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and protease inhibitors due to its carbamate and cyano functional groups.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective reactions to introduce the (R)-configured α-carbon center.
• Agrochemical Development: Serves as a building block for creating novel, enantiomerically pure pesticides and herbicides.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique properties.

Basic Information

Product Name	Carbamic Acid, n-[(1R)-1-Cyano-2-(1,1-Dimethylethoxy)Ethyl]-, 1,1-Dimethylethyl Ester
CAS No.	1673534-99-0
Molecular Formula	C13H24N2O3
Molecular Weight	256.34 g/mol
Synonyms	(R)-tert-Butyl (1-cyano-2-(tert-butoxy)ethyl)carbamate; (R)-Boc-NH-CH(CN)-CH2-O-tBu; (1R)-1-Cyano-2-tert-butoxyethyl Carbamic Acid tert-Butyl Ester; tert-Butyl N-[(1R)-1-cyano-2-(tert-butoxy)ethyl]carbamate; (R)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanenitrile; Boc-L-β-tert-Butoxy-α-cyanoalanine tert-Butyl Ester; (R)-Boc-Amino(cyano)acetic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-[(1R)-1-Cyano-2-(1,1-Dimethylethoxy)Ethyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. Our quality system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas when appropriate to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.