Description

4-Bromo-5-Fluoro-2-Methylphenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Employed in the development of chemical probes and inhibitors for studying enzyme function and protein interactions.
• Ligand Synthesis: Useful for preparing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring functionalized biaryl structures.

Basic Information

Product Name	4-Bromo-5-Fluoro-2-Methylphenylboronic Acid
CAS No.	1646842-34-3
Molecular Formula	C7H7BBrFO2
Molecular Weight	231.85 g/mol
Synonyms	(4-Bromo-5-fluoro-2-methylphenyl)boronic acid; 2-Methyl-4-bromo-5-fluorophenylboronic acid; 4-Bromo-5-fluoro-o-tolylboronic acid; B-(4-Bromo-5-fluoro-2-methylphenyl)boronic acid; 1646842-34-3; 4-Bromo-5-fluoro-2-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Fluoro-2-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture during use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.