Description

3-Bromo-4-Fluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound matters as a critical building block in modern cross-coupling reactions, enabling the efficient construction of complex biaryl structures essential for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and aryl boronic acids/esters to create complex biaryl scaffolds.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing halogenated biphenyl or heterobiaryl motifs.
• Agrochemical Compound Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific halogen-substituted aromatic systems.
• Material Science & OLED Research: Employed in the synthesis of organic semiconductors, liquid crystals, and light-emitting materials for electronic devices.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for transition metal catalysis or functionalized monomers for polymer chemistry.

Basic Information

Product Name	3-Bromo-4-Fluorophenylboronic Acid Pinacol Ester
CAS No.	1646842-16-1
Molecular Formula	C₁₂H₁₅BBrFO₂
Molecular Weight	301.96 g/mol
Synonyms	3-Bromo-4-fluorobenzeneboronic acid pinacol ester; (3-Bromo-4-fluorophenyl)boronic acid pinacol ester; 2-(3-Bromo-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Bromo-4-fluorophenyl-Bpin; B-(3-Bromo-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Br-4-F-C₆H₃-Bpin; 1646842-16-1
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.