Description

Biotin-Peg11-Mal CAS NO 1646619-56-8 is a heterobifunctional polyethylene glycol (PEG) crosslinker featuring a biotin group and a maleimide (Mal) reactive group, connected by an 11-unit PEG spacer. This compound is engineered for the site-specific conjugation of biomolecules, enabling the creation of stable, well-defined bioconjugates for advanced research and diagnostics. It is an essential reagent for scientists and manufacturers in the fields of bioconjugation, targeted drug delivery, and diagnostic assay development.

Application

• Site-specific bioconjugation of peptides, proteins, and antibodies via maleimide-thiol chemistry.
• Development of targeted drug delivery systems, such as antibody-drug conjugates (ADCs).
• Functionalization of nanoparticles and surfaces for biosensor and diagnostic applications.
• Immobilization of biomolecules for affinity chromatography and pull-down assays using the high-affinity biotin-streptavidin interaction.
• Probe and linker synthesis for cellular imaging and tracking studies.
• Preparation of biotinylated therapeutic candidates for pharmacokinetic and biodistribution studies.

Basic Information

Product Name	Biotin-Peg11-Mal
CAS No.	1646619-56-8
Molecular Formula	C58H100N4O26S
Molecular Weight	1341.5 g/mol
Synonyms	Biotin-PEG11-Maleimide; Biotin-PEG11-Maleimide; Maleimide-PEG11-Biotin; Biotin-Polyethylene glycol-Maleimide (n=11); Biotinylated PEG Maleimide; 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate
EINECS	Contact for details

Quality Control

Every batch of Biotin-Peg11-Mal is manufactured under strict quality management protocols and undergoes comprehensive analytical testing. We ensure high purity and batch-to-batch consistency through advanced techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and functional integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Integrity	≥ 90% (Maleimide, Biotin)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.