Description

3,5-Dichloro-4-Fluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex halogenated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the specific halogen pattern can influence biological activity.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and in the development of new catalytic systems.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	3,5-Dichloro-4-Fluorophenylboronic Acid
CAS No.	1646614-31-4
Molecular Formula	C6H4BCl2FO2
Molecular Weight	208.82 g/mol
Synonyms	(3,5-Dichloro-4-fluorophenyl)boronic Acid; 4-Fluoro-3,5-dichlorobenzeneboronic Acid; B-(3,5-Dichloro-4-fluorophenyl)boronic Acid; 3,5-Dichloro-4-fluorobenzeneboronic Acid; (4-Fluoro-3,5-dichlorophenyl)boronic Acid; Boronic acid, B-(3,5-dichloro-4-fluorophenyl)-; 1646614-31-4
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.