Description

4-(Bromomethyl)-2-Fluorobenzenesulphonamide is a specialized aromatic sulphonamide derivative featuring both bromomethyl and fluorine substituents, making it a versatile and reactive building block for advanced synthesis. This compound is critical for medicinal chemistry and pharmaceutical research, where it serves as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Key synthetic intermediate in the development of pharmaceutical candidates, particularly sulfonamide-based drugs.
• Building block for the synthesis of potential kinase inhibitors and other enzyme-targeting molecules.
• Precursor in agrochemical research for creating new herbicides or fungicides with novel modes of action.
• Used in material science for the synthesis of functionalized polymers or advanced organic materials.
• Valuable reagent in academic and industrial research for exploring structure-activity relationships (SAR).
• Intermediate in the production of specialized dyes, pigments, or photographic chemicals.

Basic Information

Product Name	4-(Bromomethyl)-2-Fluorobenzenesulphonamide
CAS No.	1645275-47-3
Molecular Formula	C7H7BrFNO2S
Molecular Weight	268.10 g/mol
Synonyms	2-Fluoro-4-(bromomethyl)benzenesulfonamide; 4-(Bromomethyl)-2-fluorobenzenesulfonamide; Benzenesulfonamide, 4-(bromomethyl)-2-fluoro-; 2-Fluoro-4-bromomethylbenzenesulfonamide; 4-Bromomethyl-2-fluorobenzenesulphonamide; 1645275-47-3; 4-Bromomethyl-2-fluorobenzene-1-sulfonamide
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-2-Fluorobenzenesulphonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.