Description

Methyl4-((2S,4S)-4-Ethoxypiperidin-2-Yl)Benzoate CAS NO 1644667-61-7 is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical synthesis. This compound matters for its role as a key intermediate in the development of targeted therapeutics, offering precise stereochemical control essential for drug efficacy and safety. Pharmaceutical R&D and fine chemical manufacturers need it for producing active pharmaceutical ingredients (APIs) in areas such as oncology and central nervous system (CNS) disorders.

Application

• Key chiral intermediate in the synthesis of novel pharmaceutical Active Pharmaceutical Ingredients (APIs).
• Building block for research and development of small molecule drug candidates, particularly in oncology and neurology.
• Precursor in the preparation of proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules.
• Used in asymmetric synthesis to introduce the (2S,4S)-4-ethoxypiperidin-2-yl moiety into complex molecular architectures.
• Intermediate for process chemistry and scale-up studies in fine chemical production.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Methyl4-((2S,4S)-4-Ethoxypiperidin-2-Yl)Benzoate
CAS No.	1644667-61-7
Molecular Formula	C15H21NO3
Molecular Weight	263.33 g/mol
Synonyms	Methyl 4-[(2S,4S)-4-ethoxypiperidin-2-yl]benzoate; Benzoic acid, 4-[(2S,4S)-4-ethoxy-2-piperidinyl]-, methyl ester; (2S,4S)-Methyl 4-(4-ethoxypiperidin-2-yl)benzoate; (2S,4S)-4-(4-Ethoxypiperidin-2-yl)benzoic acid methyl ester; 1644667-61-7; Methyl 4-((2S,4S)-4-ethoxypiperidin-2-yl)benzoate
EINECS	Contact for details

Quality Control

Our Methyl4-((2S,4S)-4-Ethoxypiperidin-2-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.