Description

2-(5-Chloro-2-(Trifluoromethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly for the development of novel active ingredients and functional molecules. We supply this key intermediate with a focus on batch-to-batch consistency and reliable global logistics.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-couplings for synthesizing novel drug candidates, especially those containing trifluoromethoxy and chloro-substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motifs can contribute to biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: An essential reagent for fine chemical and custom synthesis houses serving diverse R&D and scale-up projects.

Basic Information

Product Name	2-(5-Chloro-2-(Trifluoromethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1643467-83-7
Molecular Formula	C13H15BClF3O3
Molecular Weight	322.52 g/mol
Synonyms	5-Chloro-2-(trifluoromethoxy)phenylboronic acid pinacol ester; (5-Chloro-2-(trifluoromethoxy)phenyl)boronic acid pinacol ester; 2-(5-Chloro-2-(trifluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Chloro-2-trifluoromethoxyphenylboronic acid pinacol ester; Pinacol (5-Chloro-2-(trifluoromethoxy)phenyl)boronate
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Chloro-2-(Trifluoromethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is produced and tested under strict quality management protocols to ensure high purity and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.