Description

2-Amino-4-Bromo-5-Methylbenzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique halogenated aniline structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the bromine atom for further functionalization.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, color-fast azo dyes and complex organic pigments.
• Ligand and Catalyst Development: The amino and nitrile groups make it a useful scaffold for designing novel chelating ligands and organocatalysts.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Amino-4-Bromo-5-Methylbenzonitrile
CAS No.	1643156-28-8
Molecular Formula	C8H7BrN2
Molecular Weight	211.06 g/mol
Synonyms	4-Bromo-5-methyl-2-aminobenzonitrile; 2-Amino-4-bromo-5-methylbenzonitrile; 5-Methyl-2-amino-4-bromobenzonitrile; Benzonitrile, 2-amino-4-bromo-5-methyl-; 4-Bromo-2-cyano-5-methylaniline; 2-Cyano-4-bromo-5-methylaniline; 4-Bromo-5-methylanthranilonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Bromo-5-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research under ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.