Description

2-(1-Methanesulfonylazetidin-3-Ylidene)Acetonitrile is a high-value, advanced pharmaceutical intermediate featuring a unique azetidine scaffold with a methanesulfonyl and nitrile functional group. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules with potential therapeutic applications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for constructing complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in programs targeting kinase inhibition or protease modulation.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization stages to explore structure-activity relationships (SAR) and improve pharmacokinetic properties.
• Agrochemical Development: Serves as a precursor for creating new active ingredients with herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways due to its reactive nitrile group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API (Active Pharmaceutical Ingredient) batches.

Basic Information

Product Name	2-(1-Methanesulfonylazetidin-3-Ylidene)Acetonitrile
CAS No.	1638759-68-8
Molecular Formula	C7H10N2O2S
Molecular Weight	186.23 g/mol
Synonyms	2-(1-Methanesulfonyl-3-azetidinylidene)acetonitrile; 2-(1-Methylsulfonylazetidin-3-ylidene)acetonitrile; Acetonitrile, 2-(1-methanesulfonyl-3-azetidinylidene)-; 1-Methanesulfonyl-3-(cyanomethylene)azetidine; 3-(Cyanomethylene)-1-(methylsulfonyl)azetidine; (1-Methylsulfonylazetidin-3-ylidene)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(1-Methanesulfonylazetidin-3-Ylidene)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full batch traceability are provided and can be tailored to meet specific client requirements or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.