Description

2-(3-Fluoroazetidin-1-Yl)Ethan-1-Ol is a high-value fluorinated azetidine derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in introducing both a fluorinated heterocycle and a hydroxyl-terminated side chain, enabling precise modulation of molecular properties in target compounds. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, especially in kinase inhibitors, CNS-active compounds, and anti-infective agents.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides where the fluorinated azetidine moiety improves efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with tailored surface properties.
• Chemical Biology Probes: Utilized to create fluorinated probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects requiring fluorinated heterocyclic architectures.

Basic Information

Product Name	2-(3-Fluoroazetidin-1-Yl)Ethan-1-Ol
CAS No.	1638364-08-5
Molecular Formula	C5H10FNO
Molecular Weight	119.14 g/mol
Synonyms	2-(3-Fluoroazetidin-1-yl)ethanol; 1-(2-Hydroxyethyl)-3-fluoroazetidine; 3-Fluoro-1-(2-hydroxyethyl)azetidine; 2-(3-Fluoro-1-azetidinyl)ethanol; 3-Fluoroazetidine-1-ethanol; 2-(3-Fluoroazetidin-1-yl)ethan-1-ol; 1638364-08-5; FC-8423 (Potential Research Code)
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Fluoroazetidin-1-Yl)Ethan-1-Ol is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. Certificates of Analysis (COA) with full analytical data are provided for each shipment, and custom purity grades or analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and may be incompatible with strong acids and strong oxidizing agents. Keep away from heat and ignition sources. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.