Description

3-(Acetamido)-4-Fluorophenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or sensors.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or inhibitors for studying biological pathways and protein function.
• Process Chemistry & Scale-Up: The pinacol ester protection enhances stability, making it suitable for multi-step synthesis and potential commercial-scale manufacturing processes.

Basic Information

Product Name	3-(Acetamido)-4-Fluorophenylboronic Acid Pinacol Ester
CAS No.	1638329-59-5
Molecular Formula	C14H19BFNO3
Molecular Weight	279.12 g/mol
Synonyms	4-Fluoro-3-acetamidophenylboronic acid pinacol ester; (3-Acetamido-4-fluorophenyl)boronic acid pinacol ester; 3-Acetamido-4-fluorobenzeneboronic acid pinacol ester; 2-(3-Acetamido-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; N-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorophenyl]acetamide; 3-Acetamido-4-fluorophenyl-Bpin; B-(3-Acetamido-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of 3-(Acetamido)-4-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.