Description

2-Bromo-1-Fluoro-3,4-Dimethoxybenzene is a high-purity, multi-functional halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for asymmetric catalysis and cross-coupling reactions.
• Polymer & Resin Modifier: Acts as a monomer or cross-linking agent to introduce halogen functionality into polymers, altering their flame-retardant and physical properties.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.

Basic Information

Product Name	2-Bromo-1-Fluoro-3,4-Dimethoxybenzene
CAS No.	1637490-67-5
Molecular Formula	C8H8BrFO2
Molecular Weight	235.05 g/mol
Synonyms	1-Bromo-2-fluoro-4,5-dimethoxybenzene; 3-Bromo-4-fluoro-1,2-dimethoxybenzene; 2-Bromo-1-fluoro-3,4-dimethoxybenzene; 4,5-Dimethoxy-2-bromofluorobenzene; 2-Fluoro-3,4-dimethoxybromobenzene; Benzene, 2-bromo-1-fluoro-3,4-dimethoxy-; (2-Bromo-1-fluoro-3,4-dimethoxyphenyl)
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Fluoro-3,4-Dimethoxybenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.